Abdominal aortic aneurysms may be associated with elevated triglyceride levels.
Palm oil, a common ingredient in many ultra-processed foods, has been identified as a potential contributor to the development and complications of abdominal aortic aneurysms (AAAs).
This oil, which is often used as a cheap substitute for butter or other refined vegetable oils, is abundant in foods such as meat, milk, cheese, and particularly palm oil. Palmitate, the most common saturated fatty acid found in both animals and plants, is particularly prevalent in palm oil.
Recent research conducted by the University of Michigan has shown that high levels of triglycerides, which are associated with palmitate, play a direct and pathogenic role in the development, growth, and rupture of AAAs.
The study revealed that elevated triglycerides and related fatty acids, particularly palmitate, impaired the maturation and activity of lysyl oxidase, a critical enzyme that maintains the structure and integrity of the aortic wall. Mice with elevated triglyceride concentrations developed more severe complications consistent with aortic rupture, with moderate elevations accelerating aneurysm formation and higher levels leading to aortic dissection.
These findings suggest that consuming foods high in palm oil and palmitate may increase the risk of developing AAAs, a condition more common in men and people age 65 and older, and usually caused by atherosclerosis.
To prevent the development and complications of AAAs, it is recommended to avoid ultraprocessed foods such as sweets, refined grains, fried foods, unhealthy oils (including palm oil), fatty and processed meats, high-fat dairy, processed snacks, and alcohol. Healthy options include leafy greens, black beans, fresh fruit, white meat chicken and fish, oils like olive oil, flaxseed oil, fish oil, and canola oil, and fruits and vegetables rich in fiber and antioxidants (avoid fruit juices high in sugar).
For more tips on lowering triglycerides, see what cardiologist Dr. Elizabeth Klodas recommends. It's important to note that specific author names of studies investigating the role of triglycerides in the development, growth, and rupture of AAAs are not provided here.
Signs of an AAA include abdominal pain, back pain, groin pain, and a pulsating feeling in the abdomen. If the aneurysm ruptures, massive bleeding can cause death within minutes. An AAA is a bulge in the part of the aorta that travels through the abdomen, which forms in an area where the aorta's wall has grown weak, putting it at risk of bursting under the constant pressure of blood flow.
In light of these findings, it's essential to be mindful of the foods we consume and their potential impact on our health. By making healthier choices, we can reduce our risk of developing AAAs and other related complications.
