NFL showdown in Sao Paulo: Chiefs vs. Chargers forecast, odds, and timing, according to a model with a winning record of 31-15
The Kansas City Chiefs and the Los Angeles Chargers are gearing up for an exciting showdown in the 2025 NFL Sao Paulo Game, scheduled to take place on Friday, Sept. 5 at Neo Quimica Arena in Sao Paulo, Brazil.
The Chargers, who finished behind the Chiefs in the 2024 AFC West standings with a 11-6 record, have had a strong showing against their rivals recently. They have covered the spread in three of their last four meetings with the Chiefs.
The Chargers' impressive 2024 season saw them go 12-5-0 ATS (against the spread), a stark contrast to the Chiefs' performance, who finished with a 8-9-0 ATS record.
Patrick Mahomes, the Chiefs' quarterback, has a strong record against the Chargers, throwing for 3,270 yards with 27 touchdowns and seven interceptions in 12 games. However, the model suggests that one side of the spread is the better value for the Chargers vs. Chiefs game.
The Chargers' defensive unit, led by Teair Tart's critical blocks and sacks, played a pivotal role in their victory over the Chiefs in the game on September 5, 2025, securing a 27-21 win.
Injury news for the Chiefs sees receiver Rashee Rice suspended for six games, while the Chargers have Najee Harris active for the match, though they are starting rookie Omarion Hampton at running back.
The over/under for total points scored in the Chargers vs. Chiefs game is set at 47.5 points. Interestingly, the model predicts that the total points scored in the game will go Under, hitting 65% of the time.
Kickoff for the highly anticipated match is set for 8 p.m. ET, and fans can catch all the action on YouTube.
The Chiefs, who finished the 2024 season atop the AFC West division with a 15-2 record, are currently 3-point favorites in the latest Chargers vs. Chiefs odds.
The Chargers' 2024 breakout receiver, Ladd McConkey, posted over 1,100 yards in his rookie campaign, adding another offensive threat for the Chargers to utilise.
This promises to be an exciting game, with both teams eager to start their 2025 seasons on a high note. Stay tuned for more updates as we approach the kickoff.
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